AHW Awards $3.9 Million for 66 Health Improvement Projects

January 21, 2025 Posted by AHW Endowment

The Advancing a Healthier Wisconsin Endowment (AHW) is excited to announce the 66 new projects selected for Seed Grant funding. The projects focus on improving health and advancing health equity across Wisconsin.

AHW’s Seed Grants support initiatives designed to lay the groundwork for longer-term efforts to address Wisconsin’s leading health challenges. The grants, each up to $50,000, were awarded through a competitive application process and approved for funding by the Medical College of Wisconsin (MCW) Consortium on Public and Community Health, the AHW Research and Education Advisory Committee, and the MCW Board of Trustees.

“The Advancing a Healthier Wisconsin Endowment continues to develop strong partnerships throughout Wisconsin to improve the health of the people and communities we serve,” said AHW Director Jesse Ehrenfeld, MD, MPH. “This latest round of Seed Grant funding further demonstrates the successful formula we’ve used throughout our 20-year history to propel the best ideas for maximizing the health of our friends and neighbors throughout the state and beyond.”


Seed Grant Funding for a Healthier Wisconsin

AHW awarded 66 grants amounting to $3,879,305 that will fuel 21 community-led projects throughout the state, 32 projects led by MCW faculty, and 13 projects shepherded by MCW post-doctoral researchers with faculty supervision. The Seed Grant awards will take effect in January 2025.

Community-based organizations receiving AHW Seed Grants work with MCW faculty members to carry out their community-led projects collaboratively. Community-led projects receiving AHW funding represent 36 Wisconsin counties, with eight projects impacting the entire state. These projects include initiatives devoted to housing security; mental health services; healthy food access; suicide prevention; refugee and immigrant integration programs; sexually transmitted infection prevention and care; and maternal and child health.

Among the MCW projects receiving AHW funding are studies focused on the diagnosis and treatment of opioid use disorders; spinal cord and traumatic brain injury; liver disease; Alzheimer’s disease; epilepsy; and cancer.

Use the links below to visit each project’s summary page and learn more.


2025 AHW Seed Grant Recipients

Health-Focused Research

The Role of Xpr1 Genetic Variants in Resident Cardiac Macrophage Seeding
Principal Investigator: Caitlin O'Meara, PhD, Physiology

Finding Peace for Youth Suicide Loss Survivors
Principal Investigator: Sara Kohlbeck, PhD, MPH, Psychiatry and Behavioral Medicine

Transcriptional Effects of Oxycodone in Prefrontal Cortex: Focus on Neurons that Drive Drug Seeking
Principal Investigator: Christopher Olsen, PhD, Pharmacology and Toxicology

Impact of Sucralose Consumption During Pregnancy
Principal Investigator: Stephanie Olivier-Van Stichelen, PhD, Biochemistry

Establish and Validate a Model of Concomitant Neurotrauma
Principal Investigator: Antje Kroner-Milsch, MD, PhD, Neurosurgery

Preclinical Fluorescent Kinetic Modeling to Identify Viability Biomarkers for Liver Transplantation
Principal Investigator: Joohyun Kim, MD, PhD, Surgery

Using AI-Based Brain Model of Story Comprehension to Reveal MCI in Early Alzheimer’s
Principal Investigator: Andrew Anderson, PhD, Neurology

Pathophysiological Understanding for the Development of Biomarkers and Intervention for MASH
Principal Investigator: Achuthan Sourianarayanane, MD, Medicine

Oxytocin and Traumatic Injury: Delineating the Neural and Psychological Pathway to Resilience
Principal Investigator: Carissa Tomas, PhD, Institute for Health and Equity

Pharmacogenomic Mediators of Immunotherapy Resistance and Toxicity
Principal Investigator: Callisia Clarke, MD, MS, Surgery

Developing a Deep Learning Model for Predicting Seizure Generating Networks in Focal Epilepsy
Principal Investigator: Vahab Youssofzadeh, PhD, Neurology

Modeling Human Cell Cycle Dysregulation in Cancer for Drug Discovery
Principal Investigator: Ranjan Dash, PhD, Biomedical Engineering

MRI Connectivity and Machine Learning for Epilepsy Classification and Treatment Prediction
Principal Investigator: Pradeep Javarayee, MD, Neurology

Neuroimaging Markers of Semantic Impairment in MCI
Principal Investigator: Leonardo Fernandino, PhD, Neurology

Epigenetic Alterations Initiated by Gender-Affirming Testosterone in Breast Tissue
Principal Investigator: Angela Mathison, PhD, Surgery

Optic Nerve Regeneration Driven by Hypertranscription
Principal Investigator: Matthew Veldman, PhD, Cell Biology, Neurobiology and Anatomy

Chronic Tibial Neuromodulation Model Development
Principal Investigator: James Hokanson, PhD, Biomedical Engineering

Identification of Cell-Type Specific Gene Programs Dysregulated by Binge Alcohol Withdrawal
Principal Investigator: Jennifer Tuscher, PhD, Pharmacology and Toxicology

Evaluation of Pilot Hydroponics STEM Program Apprenticeship
Principal Investigator: Laura Cassidy, MS, PhD, Institute for Health and Equity

Electrical Pacemakers for Stem Cell-Derived Striated Muscle Models
Principal Investigator: Brian Lin, PhD, Cell Biology, Neurobiology and Anatomy

Cardioprotective Signaling in Diabetic-Induced Human Heart Cell Injury
Principal Investigator: Xiaowen Bai, MD, PhD, Cell Biology, Neurobiology and Anatomy

Blood Monocyte and Microglia Morphological Changes as Markers of Stress and Addiction
Principal Investigator: Constanza Garcia Keller, PhD, Pharmacology and Toxicology

Catalyzing Research on the Health Equity Impacts of Community Land Trusts in Wisconsin
Principal Investigator: Kirsten Beyer, PhD, MPH, MS, Institute for Health and Equity

MRI-Based Radiomic Analysis for Diagnosis and Prognosis in Degenerative Cervical Myelopathy
Principal Investigator: Aditya Vedantam, MD, Neurosurgery

Supporting Equitable Access to Research through the Use of a Shortened Consent Form
Principal Investigator: Ryan Spellecy, PhD, Research Office

Reinnervation Failure in Targeted Muscle Reinnervation: Influence of Chronic Axotomy and Nerve Size
Principal Investigator: Gwendolyn Hoben, MD, PhD, Plastic Surgery

Policy and Practice Related to Temporary Extension of Hours for On-Premises Alcohol Consumption
Principal Investigator: Constance Kostelac, PhD, MS, Institute for Health and Equity

Cutaneous Targets for Treating Chemotherapy-Induced Neuropathic Pain
Principal Investigator: Cheryl Stucky, PhD, Cell Biology, Neurobiology and Anatomy

Cell-Free DNA Analytical Validation Supporting Small Blood Volume Test for Infants and Neonates
Principal Investigator: Michael Mitchell, MD, Surgery

Screening for Chloride Channel 6 (CLC-6) Inhibitors as Novel Antihypertensives
Principal Investigator: Evgenii Chulkov, PhD, Cell Biology, Neurobiology and Anatomy

Inactivating SARM1 as a Therapeutic Avenue to Treat Parkinson’s Disease
Principal Investigator: Prince Joshi, PhD, Cell Biology, Neurobiology and Anatomy

Definition of Immunocyte Populations Associated with Immune Phenotypes and Putative R1D Endotypes
Principal Investigator: Amina Bedrat, PhD, Pediatrics

Novel Monocyte Populations and Type 1 Diabetes Susceptibility
Principal Investigator: Tarun Pant, PhD, Pediatrics

Targeting Hippocampal Plasticity and Inflammation in Sickle Cell Disease to Improve Cognition
Principal Investigator: Vanessa Ehlers, PhD, Cell Biology, Neurobiology and Anatomy

IL-39/IL-39R Signaling Drives Acute Graft-Versus-Host Disease Pathogenesis
Principal Investigator: Denggang Fu, PhD, Microbiology & Immunology

Understanding the Role of Genomic ExoDNA on Pre-Metastatic Niche Establishment in Ovarian Cancer
Principal Investigator: Fnu Mona, PhD, Obstetrics & Gynecology

Targeting TRPA1 Regulation by Heat Shock Proteins for Post-Surgical Pain
Principal Investigator: Jonathan Enders, PhD, Cell Biology, Neurobiology and Anatomy

Exploring Nuclear Architectural Changes in Pancreatic Cancer for Precision Therapy
Principal Investigator: Gareth Pollin, PhD, Surgery

Molecular Regulators of Mammary Epithelial Cell State Instability in Breast Tumorigenesis
Principal Investigator: Priyanga Jayakrishnan, PhD, Surgery

Au-Phagic Nanozyme for Inflammatory Breast Cancer (IBC) Targeted Therapy
Principal Investigator: Sayantan Sinha, PhD, Biomedical Engineering

Assessing the Role of Immune Cells in Factor V Leiden-Associated Pregnancy Complications
Principal Investigator: Sarika Gunjan, PhD, Pathology

Exploring the Loss of O-GlcNAcylation to POMC Pre-mRNA Intron Splicing to Reduce ACTH Secretion
Principal Investigator: Adam Knier, PhD, Biochemistry


Health Workforce Education and Development

Wisconsin Health Career Lab: A Novel Approach to Upstream Workforce Development
Principal Investigator: Andrew Klein, MD, Radiology

Vaccinating Parents and Siblings of Pediatric ED Patients, a Novel Method to Improve Vaccine Equity
Principal Investigator: Shannon Baumer-Mouradian, MD, Pediatrics

Engaging VPIT to Enhance Emergency Resident Training in Telehealth (E-VERT)
Principal Investigator: Thomas Yang, MD, Emergency Medicine

Wisconsin's Behavioral Healthcare Future: Bettering Our Systems through Peer Recovery Coach Training
Primary Community Organization: Arbor Place, Inc.
Primary Academic Partner: Felice Borisy-Rudin, JD, PhD, Pharmacology and Toxicology

HCET Provider Education Project: STI Masterclass (STIM)
Primary Community Organization: Health Care Education & Training, Inc.
Primary Academic Partner: Jennifer Walsh, PhD, Center for AIDS Intervention Research

Transforming Patient Interactions: A Performance Improvement Approach to Health Literacy
Primary Community Organization: Wisconsin Medical Society
Primary Academic Partner: Corina Norrbom, MD, Regional Campus-Central Wisconsin

Empowering Sauk County's Public Health Workforce with AI Tools for Enhanced Efficiency and Equity
Primary Community Organization: Public Health Sauk County
Primary Academic Partner: Stacee Lerret, PhD, Pediatrics

Community-Led Mental Health Transformation on Milwaukee's Southside
Primary Community Organization: Saint Adalbert Congregation
Primary Academic Partner: Courtney Barry, PsyD, MS, Psychiatry and Behavioral Medicine

Public and Community Health Improvement

Health and Housing Insecurity among Milwaukee County’s Older Adults
Primary Community Organization: Community Advocates, Inc.
Primary Academic Partner: David Nelson, Ph.D., MS, Family Medicine

YCare: Supporting Young Caregivers in Amyotrophic Lateral Sclerosis (ALS) Families
Primary Community Organization: University of Wisconsin-Milwaukee
Primary Academic Partner: Courtney Barry, PsyD, MS, Psychiatry and Behavioral Medicine

Health Videos as a Culturally Sound Approach to Integration among Refugee and Immigrant Populations
Primary Community Organization: University of Wisconsin-Milwaukee
Primary Academic Partner: Fabrice Jotterand, PhD, Institute for Health and Equity

Milwaukee County Community Mental Health Navigation Initiative
Primary Community Organization: Mental Health America of Wisconsin
Primary Academic Partner: Leslie Ruffalo, PhD, Family Medicine

Nourishing Futures: Enhancing Maternal Child Health through Nutrition and Education
Primary Community Organization: Great Rivers United Way
Primary Academic Partner: Abbey Kruper, PsyD, Obstetrics & Gynecology

CAtCH Project: Data Integration for Rapid Crisis Response
Primary Community Organization: NorthLakes Community Clinic
Primary Academic Partner: Fabrice Jotterand, PhD, Institute for Health and Equity

Partnerships for Success: Innovative Health Support for Young Parents in Schools
Primary Community Organization: Madison Metropolitan School District
Primary Academic Partner: Mochamad Nataliansyah, PhD, MD, MPH, Psychiatry and Behavioral Medicine

SSM Heart Math and Trauma Informed Care Suicide Prevention Training
Primary Community Organization: SSM Health
Primary Academic Partner: David Nelson, PhD, MS, Family Medicine

211 Wisconsin/WIRE Validated Screening Pilot
Primary Community Organization: 211 Wisconsin, Inc
Primary Academic Partner: Constance Gundacker, MD, MPH, FAAP, Pediatrics

Identifying Pathways to Implement the Help Me Grow Model within Health Systems
Primary Community Organization: First 5 Fox Valley
Primary Academic Partner: Jennifer Koop, PhD, ABPP, Neurology

Integrity for Data Equity and Accuracy (IDEA)    
Primary Community Organization: WHA Foundation, Inc.
Primary Academic Partner: Mochamad Nataliansyah, PhD, MD, MPH, Surgery

Minobiimaadiziiwin-Good Mental Health in Community-Based Qualitative Research Storytelling Program 
Primary Community Organization: Waaswaaganing Institute of Indigenous Teaching and Learning
Primary Academic Partner: Brian Jackson, PhD, Institute for Health and Equity

Ozaukee Food Alliance Fresh Foods/Food as Medicine Initiative
Primary Community Organization: Ozaukee Food Alliance
Primary Academic Partner: Corina Norrbom, MD, Regional Campus-Central Wisconsin

Nurturing the Nurturers
Primary Community Organization: The Doula Village MKE
Primary Academic Partner: Christopher Simenz, Ms, PhD, Institute for Health and Equity

Empowering Community Health
Primary Community Organization: Green County Development Corporation
Primary Academic Partner: Katinka Hooyer, PhD, Family Medicine

Empowering Wisconsin Faith-Based Groups to Combat Elderly Isolation and Depression
Primary Community Organization: Health Equity Leadership Partnership Global
Primary Academic Partner: Jamila Kwarteng, PhD, MS, Institute for Health and Equity

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